Hey there! Wholesomealive is reader-supported. We may earn a small commission from affiliate links at no extra cost to you. Your support helps us create great content. Thank you!

Best Cream For Sciatica Pain: 9 Effective Home Remedies for Sciatica Pain

Sciatica is characterized by numbness and stabbing pain in the buttocks, hips, or on one side of the leg. Typically, sciatica results from an injury. Sometimes, sciatica pain can be relieved by applying heat or ice. Other times, it requires prescription medications or topical creams.

However, what is the best cream for sciatica pain?

Sciatica is the root cause of back pain in most Americans. People may experience pain in varying degrees. Some people can cope with sciatica pain quite well, while others find it quite challenging. In order to cope with this stabbing pain, they use heat patches, injections, and topical creams.

In extreme cases of sciatica, nerve removal is needed, but topical creams work in mild cases. Here, I’ve compiled a list of the 9 most effective and widely used best creams for sciatica. Getting them is simple, and they go a long way to alleviating your pain. I will show you how!

Table of Content

Best Cream For Sciatica Pain

You can get immediate relief for sciatica pain with oral medications or topical treatments. Sciatica medicines can be applied topically as creams, gels, and oils. Some therapies may spread your blood vessels and calm your blood flow, while others may more effectively address your specific needs.

After reviewing and analyzing customer satisfaction, I have developed a list of the top 9 products you might find interesting in Best Cream For Sciatica Pain.

Penetrex (Fast Acting, Effective Sciatica Pain Reliever Cream)

Penetrex is the most intensive pain relief cream. It is one of the best muscle pain relievers that work wonders on sciatica-related pain. It is most popular among people with persistent discomfort, tingling, and itching in their legs, backs, and hips. Indeed, it acts as an anti-inflammatory agent. It addresses the root cause of the discomfort or pain and eliminates it for good.

Penetrex Joint & Muscle Therapy

This cream is an easy-to-use pain reliever that can be used alone or in conjunction with other therapies, such as heating pads, arthritis gloves, ice packs, massagers, or anything else your doctor recommends.

The affected area(s) should be applied to and then massaged for approximately two minutes to use Penetrex effectively. The amount of cream to use should be sufficient to massage the cream over the entire area smoothly and comfortably. Moreover, you can use a back pain massager to rub it.

Use the cream two to three times per day on the affected area for immediate results, and rub the cream around the roots. It typically takes 7 to 10 days to stop acute and chronic symptoms, so repeat the treatment every day for that long.

Among the best aspects of Penetrex is its 8 years of research behind it. Moreover, this is an entirely cruelty-free product, and no animals were harmed in creating it.

Active Ingredient in Penetrex

  • Arnica
  • Dimethicone
  • Choline
  • Cinnamomum Camphora (Camphor)
  • MSM(DMSO2)
  • Mentha Piperita (Peppermint) Oil
  • Vitamin B6
  • Boswellia Serrata
  • Glucosamine
  • Helianthus Annuus (Sunflower) Seed Oil
  • Aloe Barbadensis (Aloe Vera) Leaf Extract

Summary of Top Features

  • Varnishing smell (light, pleasant peppermint scent)
  • Deep relief
  • Non-staining
  • Non-greasy
  • No burning
  • Easy to apply.
  • Travel-friendly size and packaging
  • Gentle on the eyes.
  • Paraben-free


  • Currently unavailable
  • Allergic to some people
  • Mild side effects

Puriya Ultra Sports Cream (Best Cream For Diabetic Sciatica)

Puriya Ultra Sports Cream is one of the fast-acting muscle and joint pain relievers for sports injuries. It works best for sciatica pain and gives instant relief from pain. It goes well on legs, arms, knees, and ankles. In short, it is the best cream option for neurological issues and sports-related injuries.

Puriya Ultra Sports Cream (Best Cream For Diabetic Sciatica)

Natural ingredients are exclusively used to make this product in the US. It is incredibly effective in reducing discomforts related to the sciatic nerve. It relieves several symptoms such as aching, nerve burning, itching, and tingling. The cream works by inducing deep penetration into the affected area, providing instant pain relief.

Besides relieving pain, it works as a natural healing formula, which can eliminate chronic pain permanently. Also, it is 100% cruelty-free and contains no artificial materials, which can impact its quality. The cream is also quick to absorb into the skin, which gives it a refreshing feeling.

In order to alleviate discomfort, massage the area 3-5 times daily. If you have severe pain, apply the cream three times within five minutes and repeat the dosage daily three times.

Among their key benefits are relieving nerve and sciatica pain due to diabetic neuropathy. As well as being non-burning, it is suitable for people with diabetes with nerve damage who cannot feel when they are overheating.

Active Ingredient

  • Methylsulfonylmethane* (MSM) 
  • Helianthus Annuus (Sunflower) Seed Oil
  • Menthol
  • Stearic Acid
  • Citrus Limon (Lemon) Fruit Extract
  • Citrus Aurantium Dulcis (Orange) Fruit Extract
  • Elaeis Guineensis (Palm) Oil
  • Lavandula Angustifolia (Lavender) Flower Oil
  • Sodium Hydroxide
  • Citric Acid

Summary of Top Features

  • Non-Greasy
  • Non-burning
  • Non-Stinky
  • No Artificial Fragrances 
  • Long-lasting relief
  • All-natural ingredients


  • It offers immediate relief of sciatica pain, but it takes a while to heal it.

Arnica Gel Cream (Budget Friendly And Effective Nerve Pain Reliever)

Along with the Puriya and Penetrex brands, Arnica is another effective pain-relieving gel cream. 

Made in Italy, Arnica Gel Cream has an extra cooling effect and is made with extra strength. With its soothing properties, it gives relief to the tender sciatic nerve.

Real Relief Arnica Cream 4 oz Soothing Cream

Research and clinical studies have proven that gel creams can improve circulation, reduce inflammation, and calm skin. 

Additionally, the gel contains essential oils like peppermint and eucalyptus that have antibacterial properties and ease inflammation, including tingling and burning sensations caused by sciatica. 

Also, it is helpful for athletes who suffer from musculoskeletal or neurological injuries. In addition, it reduces the irritation caused by insect bites.

Likewise, it is pleasant to smell as well as relaxing. The cream is also simple to use. To use the cream, apply it to the painful area 2 times a day.

Active Ingredients

  • Aqua
  • Helianthus Annuus (sunflower) seed oil
  • Arnica Montana flower extract
  • Glycerin
  • Citric acid
  • Limonene
  • Linalool
  • Tocopherol

Summary of Top Features

  • Perfect for a sportsman
  • Great for muscle massaging
  • Dermatological tested 
  • Perfect for traveling
  • Quick-relief
  • Suitable for sensitive skin
  • Paraben-free

Real Relief Arnica Cream

Check Latest Price on Amazon


  • Some people may be allergic to it
  • Temporary relief

Neuropathy Nerve Pain Relief Cream

Neuropathy nerve pain relief cream is one of the best creams for sciatica pain. It is formulated with ingredients that have been clinically proven to provide pain relief for muscles and joints.

The cream absorbs quickly and provides targeted relief to the affected area. Its effects are efficient for neck, back, hip, knee, shoulder, legs, joints, muscles, and nerve pain.

Neuropathy Nerve Pain Relief Cream

It is made with powerful ingredients that promise effective relief, which means you only need a little to reap maximum and lasting benefits.

Neuropathy is carefully formulated to provide pain relief, moisturize, and regenerate the skin. In fact, it allows the blood flow to improve, thereby soothing muscles and nerves. It also supports the skin’s natural healing process. Overall, it promotes healthy skin and blood circulation. 

Additionally, it is fast, easy to use, and affordable. The cream should be applied evenly across the target area after cleaning the affected area. Apply it properly by massaging it until it is fully absorbed. Continue doing so 3 to 4 times a day until the pain disappears. 

Active Ingredients

  • Arnica
  • Vitamin B6
  • Vitamin E
  • MSM
  • Menthol

Summary of Top Features

  • Rejuvenation
  • Immediate Relief
  • A Natural Solution
  • Fast Absorption
  • Designed by Medical experts
  • Highly moisturized
  • Absorb quickly
  • Non-greasy
  • Pleasant Smell
  • Regulate blood circulation


  • Not good for severe sciatica pain
  • Pungent Smell

MagniLife Leg & Back Pain Relief Cream (Sooth, burning, stabbing, and Tingling)

Magnilife Leg & back pain relief cream is made by one of the top healthcare providers, Magnilife. 

Magnilife Leg and Back Pain Relief Cream are specifically designed to ease the pain of sciatica. With this product, you can get fast relief from cramping, throbbing, burning, and tingling associated with sciatica. This cream helps to relieve sciatica pain in the legs, buttocks, hips, and back.

MagniLife Leg & Back Pain Relief Cream

Furthermore, the product is made from all-natural ingredients with no added fragrances or dyes. Pain relief is accomplished with active ingredients that penetrate deeply and provide long-lasting comfort. The aloe and calendula in this cream work together to relieve pain.

You may use it with other OTC pain relievers and prescriptions. In addition, it has fewer side effects than other pain reliever creams. To use this cream, gently massage the cream into the affected area and apply liberally. For best results, do it twice daily.

Active Ingredients

  • Colocynth
  • Aloe
  • Magnesium
  • Geranium
  • Lavender
  • Chili pepper
  • Sweet
  • Calendula
  • Flower extract

Summary of Top Features

  • Non-greasy
  • Instant Relief
  • Natural ingredients
  • Safe to use on sensitive skin 
  • Free of harsh chemicals
  • Expertly crafted formulas
  • Budget-Friendly


  • Temporary pain relief
  • Poor consistency

Outback Pain Relief Cream (Best Fast Sciatica Strains Relief Cream)

Another option for sciatica pain is Outback pain relief cream. Pain relief is achieved with its natural active ingredients, beneficial for muscles, joints, and nerves. A pain relief cream developed by Outback is designed to provide quick relief from chronic pain.

Outback Pain Relief Cream

 It is beneficial for arthritis, sciatica, simple backaches, bruising, and sprains as a wonder cure. The product contains 6% camphor and 16% methanol, as well as a blend of active components that help you experience fast pain relief. 

This formula quickly absorbs into the skin and relieves throbbing nerves in the legs, neck, hips, elbows, wrists, hands, back, and knees. 

As opposed to others, it offers a cooling and warming effect to ease pain discomfort. Moreover, its oil content helps to reduce inflammation. 

Apply a small amount to the affected area and massage gently until the cream is absorbed to use the cream. Throughout the day, repeat the process twice or thrice, but not more than four times.

Active Ingredients

  • Methanol
  • Camphor
  • Melaleuca Alternifolia (Tea Tree) Leaf Oil
  • Eucalyptus Globulus Leaf Oil 
  • Fruit Extracts
  • Blue Mallee Eucalyptus
  • Vanilla

Summary of Top Features

  • Paraben-free
  • Cruelty-free
  • Increase circulation
  • Reduce inflammation
  • Natural active ingredients
  • Effective for muscles, joints, and nerves
  • Fast-acting
  • Long-lasting comfort
  • Maximum absorption
  • Natural healing and cooling effect
  • Money-back guarantee


  • Toxic to open wounds
  • Currently unavailable.
  • Avoid using around eyes and mucous membranes.

Sombra Warm Therapy Natural Pain Relieving Gel (Best Sciatica Pain Cream During Pregnancy)

There is a risk of experiencing mild to severe sciatica pain in pregnant women because the pelvis and uterus expand, touching and irritating the sciatic nerve. As if carrying a baby for 9 months wasn’t stressful enough, untreated postpartum depression can cause severe pain and ache in the hips and legs.

It can also develop into chronic pain that persists even after the baby is born and breastfeeding. Sombra warm therapy natural pain-relieving gel is an ideal option for pregnant women and breastfeeding moms.

Sombra Warm Therapy Natural Pain Relieving Gel

With its menthol and USP 6%, Sombra Warm Therapy will provide a cool as well as a warming effect on the affected area. As well as this, it has an aromatic orange scent that is relaxing and balancing.

It is US made and free of any animal testing. It provides instant relief from symptoms and inflammation of the sciatic nerve, similar to other creams on this list, and there is no side effect for pregnant or nursing women.

Additionally, it is alcohol-free since it is used a lot by nursing mothers. Apart from sciatica, you can also use it to treat arthritis, muscle injuries, and other types of backache.

Active Ingredients

  • Camphor
  • Methanol

Summary of Top Features

  • Non-greasy
  • Animal-Free
  • Ideal for pregnant ladies
  • Relaxing scent
  • Quick to absorb
  • Non-staining
  • Alcohol-free


  • Effective only for mild aches
  • May cause allergic reactions in some people

Natural Hemp Cream (Helps With Sciatica And Painful Joints)

The Natural Hemp Cream is safer and more effective than the above-mentioned pain-relieving creams. It contains a blend of pure natural ingredients, suitable for use each day and for improving mobility.

This product contains MSM, arnica, turmeric, and aloe vera. According to its manufacturers, the product is free from toxins, chemicals, or agricultural by-products. Natural CBD, which soothes nerves and relieves pain, is the active constituent of this product.

Natural Hemp Cream for Muscles

Among its many uses, this product effectively treats shoulders, legs, feet, arms, necks, and back pain. This product also feels gentle on the skin. It is a non-greasy, non-sticky cream that does not stain the skin.

It absorbs quickly into the skin and restores normal function to the nerve endings. The effect lasts for as long as a while. In addition, it alleviates discomfort without leaving behind a sticky residue.

In addition to its pain-relieving qualities, hemp cream also provides omega-3 and omega-6. Moreover, it keeps the skin supple and moisturized. It also smells deliciously of citrus oranges.

Active Ingredients

  • Aloe vera
  • Boswellia extract
  • Hemp oil
  • Menthol
  • Turmeric
  • Emu oil
  • Arnica montana

Summary of Top Features

  • Clinically tested ingredients
  • Innovative plant-based formula
  • Non-greasy
  • Lightweight
  • Non-sticky
  • Non-staining
  • Gentle on the skin
  • Fast absorption
  • Fast pain relief action
  • Muscle recovery
  • Quick to absorb
  • Long-lasting results
  • GMO-free


  • Temporary relief
  • Can cause inflammation or allergy

Sciaticream (The Best Sciatica Pain Relief Cream)

For nerve pain relief, sciaticream is the most commonly prescribed topical cream. Scientific studies have shown that natural ingredients in this cream penetrate deeply into the skin and provide immediate pain relief.

Sciatic Nerve Pain Relief Cream with Arnica

In contrast to other sciatica creams, this product provides a high level of moisturizer and antioxidants to leave the skin soft and supple.

If someone has knee or elbow pain or arthritis, it can also benefit them. Besides providing anti-inflammatory properties and relaxing effects, the product also relieves sciatica and joint pain quickly.

Manufactured put a vast body of scientific research into creating the ultimate winning recipe. It contains ingredients that are scientifically proven to provide long-lasting relief.

Among its advantages is that the formula does not require an extensive application and is strong enough to last for a long time.

Active Ingredients

  • Aloe
  • Coconut oil
  • Vitamin B12
  • Vitamin E
  • Vitamin B1, B5, & B6
  • MSM
  • Capsaicin
  • Phenoxyethanol
  • Sorbic Acid
  • Andrographis Paniculata Extract
  • Panthenol

Summary of Top Features

  • Quick-relief
  • No itching and burning
  • Hypoallergenic
  • Gentle on the skin
  • Odor free
  • Naturally soothing
  • Made of natural ingredients
  • Quick to absorb
  • Super easy to apply
  • All ingredients are scientifically proven to cure sciatica pain


  • Not safe on open wounds
  • May irritate skin
  • Irritating to the eyes
  • Not recommended for people with too sharp sciatica pain

Picking the Right Cream to Treat Sciatica Pain

Sciatica treatment involves selecting the best creams for sciatica pain. Clinically proven creams with highly effective ingredients should be your first choice. Here are some important factors to consider when choosing the best creams for sciatica pain. 

Lab Results

When choosing a cream for sciatica pain, ensure it is tested and scientifically proven to be effective. There is no doubt that all pharmaceutical products are clinically proven, but the label provides assurance that they will work and be effective. 

Price Of Cream

Sciatica is a neurological issue in the back, which means the cost for different treatments may fluctuate. If you have a budget limitation, you may want to consider more affordable options, but make sure they have been properly researched, tested and work (based on customer reviews). 

If user reviews confirm that the cream or gel works, it may be worth it to break the bank.

Composition Of Cream

Certain creams may contain ingredients that irritate your skin. To be safe, be sure to check the label before ordering. Instead, make sure to scrutinize a product before buying. 

Avoid buying a product with a label that lists a material you may be allergic to, and opt for alternatives.

What It Does

Symptoms of sciatica vary from person to person. Thus, consider what problem is being solved by the cream you’re considering buying. In addition to tingling and burning, sciatica can cause itching, stinging, and numbness as well. Make sure the topical cream you choose will address these symptoms.

How to Use Creams for Sciatica Pain?

The most effective way to relieve sciatica pain is to apply and rub cream. Use a cream that you can easily apply – and massage it downward in circular motions. You should use the proper application to prevent sciatic nerve irritation from spreading to your legs through your disk.

Gel or cream for sciatica should be applied and rubbed all over your lower back, preferably the lumbar region, while also concentrating on the rear pelvis region. In the vicinity of the posterior pelvis are the sciatica nerve roots. It is here where the pain comes from!

How to Use Creams for Sciatica Pain?

When you target higher areas of the back of the lower regions of the body, you can only temporarily turn around the problem. Pain typically begins in one part of the body before traveling to your legs and feet. Thus, massaging the root of the nerves can stop the spreading of pain. Afterward, relax the muscles and decompress the nerves.

You can help your body respond to nerve decompression by performing moderate physical activities after applying a cream or gel for sciatica pain. Your pain will subside or disappear while you are exercising moderately. Indeed, it indicates the topical medicine is working.

How Long Does It Take For Sciatica To Go Away?

Pain from sciatica is caused by overexcited nerves or inflammation. There is usually a 4 to 6-week period of discomfort, but it can last longer. If you use topical creams, you may temporarily feel better and get a temporary recovery.

A severe case of sciatica nerve damage can last up to six weeks. It usually takes 4 to 8 weeks for sciatica to heal fully – no pain, regular movement, full strength.


What Are The Best Creams For Sciatica Pain, U.K.?

Following are some best creams for sciatic pain in the U.K.

  • Magnilife leg & back pain relief
  • Sciaticream
  • Sciatica R.X. nerve cream 
  • Inmotion Hemp Pain Relief Cream Ultra Strength
  • Topricin Pain Relief Therapy Cream

You can purchase them from Amazon or another online retailer. You can also find them at local pharmacies. 

What Are The Best Medicines For Sciatica Pain?

Pain relievers, antidepressants, anticonvulsants, muscle relaxers, and steroids can help ease sciatica pain. Below are a few OTC medications for relaxing your throbbing sciatic nerve.

  • Aleve (NSAID)
  • Tylenol (Pain killer)
  • Lorzone (Muscle Relaxant)
  • Fexmid (Muscle Relaxant)
  • Gabapentin 
  • Zanaflex (Muscle Relaxant)
  • Pamelor (antidepressants)
  • Norpramin (antidepressants)
  • Lyrica (Anticonvulsant)
  • Prednisone (Anti-inflammatory)

What Are The Best Pain Patches For Sciatica?

Topical creams and medicines help to relieve sciatica pain. But using pain patches can help you to ease the pain faster and relax the pain. You can use gel/cream or lidocaine pain patches on your rear pelvis where your sciatica nerve is placed. 

By treating the area where the pain is located instead of the thigh or calf, you can control and numb the pain at its source while also soothing nearby nerves.

Below are the top few pain patches that work best for sciatica

  • Bengay Ultra Strength Pain Relieving Patch
  • Biofreeze’s Pain Relief Patch
  • Luminas 
  • Grown Science Broad Spectrum Nano CBD Patch
  • Envy CBD Relief Wraps
  • Signal Relief patch
  • CBD Infused Patch
  • iReliev TENS Mini Pain Relief Patch
  • FeelZing patch
  • Hemp Bombs CBD Patches
  • Salonpas Pain Relieving Patch

How To Cure Sciatica Permanently?

Physiotherapy is an effective way to recover from sciatica permanently. You can implement sciatica pain relief exercises in these therapies to get rid of the pain. The treatment involves physical activities, such as stretching, walking, swimming, etc. Do acrobatics every day if you want your sciatica to disappear.

What Helps Sciatica Heal Faster?

Heat and Ice alternate therapies can be used to manage sciatica pain. Heat may ease pain, while ice can reduce inflammation. The combined action can speed healing. Often, the cramps and spasms associated with sciatica can be relieved by heat or ice.

How Should I Lay With Sciatica?

Sciatica sufferers often complain of pain when they lie down. Generally, it is easier to sleep on your side or back rather than on your stomach. If you sleep on your side, it might be helpful to place a pillow between your waist and your knees, so the knees are not in direct contact with the mattress.

Concluding Remarks

Sciatica pain is the common reason for most back and leg pain in the United States. It occurs when the sciatica nerve is irritated, itched, or compressed. It passes through the buttocks to the thighs and even in the sole of the feet.

Several factors can trigger sciatic pain flare-ups. The body’s chemical make-up, immunity, and physical traits are among the elements. In general, tall people and women are more likely to develop sciatica.

However, the use of specially-blended creams can help alleviate this pain. I’ve listed the 9 best creams for sciatica pain that are sure to lessen the throbbing and stabbing of nerve pain.

Wholesomealive.com -a blog about Healthy Living