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How to Switch Zoloft from Night to Morning? Simple Solutions!

In the modern age, depression is a major disease existing globally. It is predicted that depression is the main cause of disability in countries that are highly progressive. If you are facing depression, you may know about Zoloft. Zoloft is a type of antidepressant. It is part of a group of medications known as SSRIs. Zoloft (or Sertraline) is used to treat depression, anxiety, panic attacks, and other mood disorders. 

Many people ask, ‘how to switch Zoloft from night to morning?’

You can switch Zoloft from night to morning by skipping a dose. If you always take Zoloft at 10 pm, then skip that dosage and take it the next morning. The dosage is taken according to the mental need of the patient. For some, Zoloft works best at night. For some, it works best in the morning. 

Let’s explore more about it. 

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How to Switch Zoloft from Night to Morning

How to Switch Zoloft from Night to Morning

As you know, Zoloft is an antidepressant, so one must handle its timings with care. While taking this medication, one may think about switching Zoloft from night to morning.  

If you want to switch the timing of this medicine, it is worth communicating with your doctor before taking any steps to change your Zoloft schedule. 

One other possible way to switch the timing is to skip the dose at once and then take it at the time you want to switch it as morning or evening. In this way, you can easily change the time of sertraline you are taking.

For example, let’s say you want to switch Zoloft from night to morning. Every night you take Zoloft at, for instance, 10 pm. Then you have to skip this dose and take it in the morning. Then from the next day, you can continue taking the medicine in the morning at the same time. 

Whether to switch Zoloft dosage from night to morning ultimately depends on factors like possible side effects, dosage, and how the drug affects your physical and mental health. 

So it is essential to decide how to take this medication according to its effects on your body.

Side Effects of Taking Zoloft:

Like other drugs, Zoloft also has some side effects which may affect the physical condition of the patient. 

So let’s see the downside of taking Zoloft:

  • Headache
  • Nausea
  • Diarrhea
  • Weight loss
  • Insomnia
  • Dysfunction in sexual relation
  • Lower levels of sodium in your blood.

How to Switch Times for Zoloft

No matter what time of the day you take Zoloft, its effects are the same. 

This medication is recommended by doctors to treat disorders related to the brain like:

  • Major Depressive Disorders
  • Disorders of compulsive behavior (OCD) 
  • Post-Traumatic Stress Disorder (PTSD)
  • Anxiety disorders associated with social situations
  • Panic Disorder
  • Premenstrual Dysphoric Disorder (PMDD)

If you are taking Zoloft for disorders which are mentioned above, you may be thinking about what time of day you should take this medication. It simply depends on how it personally affects you.

When you switch your dosage from night to morning, or oppositely, you may consider its impact on your physical condition. 

Some people feel drowsiness and some feel insomnia after taking  Zoloft. 

If you are feeling drowsiness and nausea, it is worth switching your dose at night

If you are facing insomnia, sexual disturbance, and urinary problem after intake of Zoloft, you must switch to morning.   

Meanwhile, it is essential to consult with your doctor when you want to switch your medicine. Your doctor will give you the best suggestion according to the side effects you are facing. 

One more important thing is that if you forget to take Zoloft, do not overtake the dosage the next day.

Best Time to Take Sertraline, Morning or Night

taking zoloft in the morning

Patients who are taking Zoloft may be wondering what is the best time to take sertraline. 

Sometimes it is best to take your antidepressant in the morning, and sometimes it is good to take it at night. 

So let’s explore something more about the best time to take sertraline.

Why is it Best to Take Zoloft in The Morning:

It is sometimes best to take antidepressants in the morning because of unwanted side effects. 

Some suggestions are below:

  • Some patients feel a disturbance in sleeping after the intake of sertraline. To prevent sleeplessness, it is best to take an antidepressant in the morning. Some people also have excessive sweating at night due to Zoloft, which hampers their sleep. 
  • Some patients experience sexual dysfunction after intake of Zoloft. For them, it is best to take this medication in the morning.
  • Do not take an antidepressant at bedtime if a patient is experiencing urinary problems, such as not controlling urine during sleep. So if you are experiencing this issue, it is worth taking Zoloft in the morning.

So, if you were wondering ‘why should you not take sertraline on a night’ the above reasons are for you.

Why is it Best to Take Zoloft at Night:

It is best to take an antidepressant near to your bedtime, because you may face some side effects such as:

  • An antidepressant may cause drowsiness in some patients. To prevent this condition, it is best to take Zoloft at night.
  • Sertraline often disturbs the digestive system and causes nausea. To reduce this issue, you can switch your dose to the night.

How to Start Taking Zoloft Again

How to Start Taking Zoloft Again

If you want to get rid of your anxiety, depression, and other depressive disorders, take one dose of Zoloft daily according to the advice of your doctor. 

If you forget to take your medicine, do not double your dosage the next day. 

If you want to stop this medication, do not do it immediately! Because it causes some expected side effects to your body such as headache, body pain, loss of appetite, less sleep, and vomiting. 

Sometimes patients want to restart taking sertraline, so it is essential to consult your doctor.

Do not restart Zoloft on your own because sertraline has some side effects. So it is worth talking to your doctor about your depressive condition before starting your medication again. You can easily start taking Zoloft again when your doctor recommends it to you.

Frequently Asked Questions (FAQs)

Should I take my Zoloft in the morning or at night?

Take your medication daily according to the doctor’s prescription. If you are experiencing some side effects such as insomnia, sexual dysfunction, and urinary problems, you can take your Zoloft in the morning. On the other hand, if you are experiencing drowsiness and nausea, you can switch your Zoloft at night.

Does sertraline work better in the morning?

Sertraline is used to reduce or treat depression and anxiety. In some conditions’  intake of Zoloft in the morning works better and is fruitful. For example, if you are facing difficulty sleeping after intake of this medication, you can take it in the morning. It simply depends on the physical condition of the patient, whether it works better in the morning or at night.

Can I restart my antidepressants?

Yes, you can start your antidepressants. If you forgot to take your medication, you can restart it as soon as possible. It is better to take an antidepressant regularly for 3 to 6 months to tolerate your depressive disorders. If you have stopped your medication and then want to start it again, you can do it by consulting your doctor. It is helpful to consult a doctor first and then start again.


It is a common question, ‘how to switch Zoloft from night to morning?’ 

An antidepressant named Zoloft is used to get rid of depressive disorders, or mainly anxiety and depression. In order to maximize its benefits and minimize any potential side effects, it is possible to switch Zoloft from night to morning or oppositely. 

Sometimes an antidepressant works better in the morning, and sometimes it results better at night. It is possible to switch Zoloft from night to morning by skipping a night dose and taking it in the morning.
However, if you want to switch the time of your medication, it is better to consult your doctor before making any changes to your treatment plan.

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