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Will Acid Rebound Go Away?

Acid rebound is a common condition that can range in severity from mild to serious. Every individual will have a unique experience of acid rebound. Likewise, everyone needs personal medical attention. 

There are many drugs for acid suppression on the market worldwide. 

Yet, the question remains: will acid rebound go away

Acid rebound will go away with prompt treatment and good insight. To know more, you have to read about the symptoms and causes of acid rebound. Along with that, you can explore and adhere to the treatment options available.

Want to know more about this topic? Herewith, this article will guide you on tits and bits of acid rebound phenomenon. 

Table of Content

What is Acid Rebound?

Usually, acid rebounds occur among patients using acid-suppressing drugs for a long time. When they stop taking their drugs, it may produce an acid rebound. 

Examples of acid-suppressing drugs include the proton pump inhibitors (PPI) like Omeprazole or Esomeprazole. (Omeprazole has other side effects too!)


What happen when you stop PPIs? According to the suggested physiology, reduced gastric acidity causes hypergastrinemia. 

Hypergastrinemia is a condition when a type of hormone called gastrin stimulates the secretion of gastric acid in the stomach. The excess gastrin in a person’s blood will alert the stomach to function in a way that makes more acid.

As a result, too much acid production following the discontinuation of PPI occurs. This excessive gastric acid production is called acid rebound. 

When stopping a PPI usage causes acid rebound, people choose to start the PPI again. As a result, a never-ending cycle can occur where further treatment will come after initial therapy.


The symptoms of acid rebound are like acid reflux. Let us look at the most typical symptoms of acid rebound. 

The most common symptom of acid rebound is heartburn. You will experience a burning chest pain that forms behind your breastbone. Later, it progresses upward to your neck and throat. It feels like food is refluxing back into the mouth most of the time. 

For the duration, heartburn can last as long as an hour or more. 

It’s often more sinister after ingesting food, lying down, or flexing your body. Meanwhile, leaning upright will cause the acid flow to empty from the esophagus. This will make you feel better.

Heartburn may be the chief complaint seen among patients. There are many other symptoms of acid rebound. Here are a few of them:

  • Nausea/ Vomiting
  • Bad breath
  • Shortness of breath 
  • Swallowing problems 
  • Erosion of tooth enamel 

Acid rebound occurs in the daytime. But, if you have a nocturnal acid rebound, you may also encounter: 

  • Persistent cough
  • Worsening asthmatic symptoms
  • Sleeping difficulties

If you have any of the symptoms listed above, you should seek help from a medical practitioner. 

Will Acid Rebound Go Away?

Let’s address the most important question now- will acid rebound ever go away? The answer is yes!

Now, how long does rebound from PPI last? First of all, acid rebounds can last from a week to several months. Acid rebounds take time to go away. 

Will acid rebound go away on its own? It may, but it takes a very long time. It may cause severe harm to your body at this time.

So, with proper treatment and precautions, an acid rebound can go away fast and never return. But, before jumping into the treatments, let’s look at the factors influencing acid rebound. This will help you better understand your condition so you take proper measures to cure it.

5 Factors Affecting Acid Rebound

Acid rebound is due to a defect in the esophageal muscle after stopping your usual drugs. 

Usually, the muscles contract after the food reaches your stomach. If it does not contract, your stomach contents ascend in reverse order into the esophagus. 

When gastric acids subside into the esophagus, it provokes acid rebound. Aspects that cause acid rebound to aggravate include:

Excessive Stress on Stomach

Stress on the stomach may cause acid rebound to worsen. Some pregnant women encounter heartburn almost every day because of this raised pressure.


Discontinuation of Acid-Suppressing Drugs

Stomach cells that produce acid multiply over several weeks of disclosure to a PPI. They produce excessive acid, leading to acid rebound.

Type of Food

The type of food you consume may also contribute to the acid rebound. For example, spicy or fried foods, caffeine, chocolate, garlic, and alcohol.

Eating Practices

Consuming foods in an excess amount, more than your usual capacity can induce acid hypersecretion.


For instance, certain drugs like antibiotics and aspirin can cause acid rebounds.

Well then, now you know why you are getting acid rebound and how it might get worse. 

‘Does acid rebound disappear?’ must be the question bothering you now. So, without further ado, let’s look at ways to diagnose and treat it.


Usually, doctors can tell based on your symptoms only. Furthermore, it is crucial to reveal your history of medical illness and medication.

  • Doctors may need to view your esophagus with flexible endoscopy.
  • Doctors will estimate the amount of gastric acid in the esophagus using the pH test.
  • They may test the esophageal muscle to check the function via a manometry test.

How to Treat Acid Rebound?

The treatment of acid rebound will be based on how much it has affected your esophagus. 

So, it is crucial to see a doctor in case of severe acid rebound. They can tell if you have any damage to your esophagus and provide treatment options. 

I’ve listed some simple treatment options you can follow to reduce the symptoms. Along with that, also some options doctors may choose.

Lifestyle Changes

Simple lifestyle changes can manage people presenting with light symptoms, such as:

  • Cessation of smoke
  • Losing weight
  • Consuming food in smaller quantities
  • Avoiding sleep right after meals
  • Avoid Certain Foods

Symptoms of acid rebound are similar to that of acid reflux. Thus, the things that relieve acid reflux can help to improve acid rebound symptoms too. 

Staying away from particular foods that trigger acid rebounds can provide comfort. These foods are: 

  • Liquor, Caffeine, and Carbonated drinks
  • Citrus fruits, such as orange and pineapple
  • Chocolate and mint
  • Fried and fatty foods, such as French fries
  • Full-fat dairy products, such as sour cream
  • Garlic and Onions
  • Spicy food

Certain foods can be consumed too that can help relieve acid rebound symptoms. Did you know even carrot juice can help relieve acid reflux?


Lifestyle modifications may permit the body to recover itself. But sometimes lifestyle changes are not enough. 


In this case, it’s good to know what medications you can take to help with acid rebound: (Remember to consult a doctor before trying any new medication)


An antacid is fast-acting, and it can downsize the quantity of acid in the stomach. Other than that, antacids won’t cure the injury formed in the esophagus.

Histamine H2-receptor Antagonists

This group of drugs acts as a long-term convenience, like PPI.

So if you were wondering, what can you take instead of PPIs, the above options are there.


All aside, for chronic acid rebound, surgery is the best treatment. It responds better among people who don’t respond or stay compliant with medications. 

Now then, is acid rebound permanent? No, it isn’t. Once acid rebound symptoms are under good control, no injury to other parts of the body will occur. 


Keep some precautions in mind in case you ever start PPIs again and think of quitting. Or for anyone who hasn’t left their acid-suppressing drug yet. 

Does acid rebound relapse with improper treatment? In regards to stopping anti-suppressing drugs, perform a step-down strategy. This strategy will suit patients that have no symptoms or do not need long-term therapy. 

The step-down strategy concerns decreasing the dose before discontinuing the medication. Remember, stopping the drugs immediately will result in an acid rebound. 

Moreover, alternative management like antacids may be beneficial to treat acid rebound. 

Common Complications  

You now may wonder, will acid rebound go away with treatment? It will, but since acid rebound can injure and damage your esophagus, there are various risks factors. The common complications are: 

  • Laryngitis
  • Chronic inflammation, also known as esophagitis
  • Ulcers 
  • Esophageal stricture
  • Cancer, also known as Barrett’s esophagus

Acid Rebound in Pregnant Women

Acid reflux and acid rebound correlate with pregnancy. Pregnant women usually undergo worsening acid reflux symptoms around the first trimester. 

Later, it deteriorates in the final trimester. The boon is that your symptoms will vanish when you deliver the baby. But, the acid rebound is not the same. 

Pregnant women assume the intake of multivitamins and drugs may harm their conception. Regardless, the acid rebound can be cured by taking their acid-suppressing drugs.

 Interestingly, PPIs are considered safe during pregnancy.

Also, pregnancy can boost the quantity of the hormone progesterone. It can force the muscles of the lower esophagus to relax. Thus, initiating acid rebound.

Other than that, stress due to a growing uterus can raise the likelihood of acid rebound. Otherwise, symptoms and treatment are all similar as per non-pregnant women. 

Most Important Step:

When acid rebound occurs, gastric acid will begin to attack the esophageal lining. 

Then, the tissue becomes destroyed someday. If you have chronic symptoms, it will impact your eating and sleeping patterns. Thus, reach your family doctor when acid rebound interrupts your everyday life. 

Even though acid rebound isn’t life-threatening, its long-term damage can be hazardous. Also, you may need powerful prescription drugs or surgery to relieve your symptoms if they get chronic.

So, remember to not delay and see a doctor!


Question: How long will acid rebound last with treatment?

Answer: With treatment, acid rebound takes about two weeks to resolve completely. The treatment, whether medication or lifestyle changes has to be followed properly for best results.

Question: How long does rebound acid hypersecretion last? 

Answer: Usually, rebound acid hypersecretion lasts more than 8 weeks. This time can vary from person to person.

Question: Can acid rebound cause diarrhea? 

Answer: Increased gastric acid production can lead to diarrhea. While most people face nausea and other symptoms, some may face diarrhea too. 


Will acid rebound go away? We are aware that your acid rebound symptoms may relapse anytime. Acid rebound will go away with proper treatment and care.

If you develop any symptoms of acid rebound, call your family doctor as soon as possible. Doctors will address your worries and assure you get the best treatment.

Keep these in mind and your acid rebound should be gone before you know it!

Hope the article has helped. 

Thank you for reading.

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