Hey there! Wholesomealive is reader-supported. We may earn a small commission from affiliate links at no extra cost to you. Your support helps us create great content. Thank you!

Spironolactone Belly Fat Loss or Gain? Balance Between 2 Controversial Factors

Want to cut extra pounds? Have you heard about the connection of spironolactone with weight loss? This article will focus on, can spironolactone belly fat loss is feasible or not?

Spironolactone is a physician-endorsed medicine first supported by the U.S. Food and Drug Administration (FDA) in 1960. In addition, Spironolactone is an extraordinary kind of water pill in a class of prescriptions called potassium diuretics.

Many water pills work in the kidneys to wipe out additional water from the body alongside sodium and potassium. Spironolactone works unexpectedly. It hinders a chemical called aldosterone, which eliminates water alongside sodium; however, it lessens potassium excretion.

Table of Content

Does Spironolactone Belly Fat Lose Possible?

No logical examination has assessed spironolactone explicitly for weight reduction. In any case, it’s a good idea that spironolactone may diminish weight in specific individuals, particularly those with high retention of fluids.

Related: Is Spironolactone Weight Gain After Stopping Real?

So, if you’re thinking, Can spironolactone help with weight loss? Then the answer is yes; it might help.

spironolactone belly fat

Spironolactone fills in as a diuretic, which implies that it makes the body eliminate additional fluids. Diminishing liquid in the body can reduce body weight.

Additionally, remember that this sort of water-weight reduction isn’t equivalent to substantial weight reduction because of a decrease of muscle to fat ratio or weight. These require great sustenance and exercise.

Weight reduction because of liquid decrease probably won’t be enduring. Diminishing body liquid to an excessive amount can lead to a lack of hydration. Moreover, when body liquid levels get back to business as usual, the weight will return.

Lastly, Spironolactone has been examined in ladies with bulging bellies because of premenstrual disorder (PMS).  Spironolactone can cause a massive improvement in these indications by diminishing liquid accumulation.

Related: Why Am I Losing Weight During Menopause?

Accordingly, a few specialists recommend spironolactone for ladies who create swelling and weight from water maintenance because of PMS. So, spironolactone belly fat is yet to be established through research.

What Are The Side Effects Of Spironolactone?

Let’s talk about the adverse effects of spironolactone! Taking any recommended drug, including spironolactone, accompanies adverse reactions. Spironolactone can cause changes in blood levels of potassium.

In case changes are extreme, this can cause death. Moreover, spironolactone can likewise interact with different medications and might be unsafe whenever taken during pregnancy.

Firstly, if you think about spironolactone weight loss results, you must read the side effects first.

  • Dizziness
  • Xerostomia(dry mouth)
  • Breath tenderness
  • Irregular menstrual periods
  • Stomach upset
  • Spironolactone bloating
  • Vomiting 
  • Diarrhea
  • Headache
  • Spironolactone loss of appetite
  • Vaginal bleeding (Post-menopausal)
  • Confusion
  • Arrhythmia
  • Difficulty in breathing
  • Flu-like symptoms
  • Unusual bleeding
  • Bruising
  • Numbness
  • Muscle pain

Does Spironolactone Cause Weight Gain?

There is no direct connection between spironolactone and weight gain. There is no clinical proof supporting the theory of acquiring extra weight caused by Spironolactone pills. Then again, most patients who have this pill will, in general, shed pounds since it is a diuretic, and spironolactone belly fat does happen.

Therefore, a few patients may encounter weight gain during the intake due to hunger pangs or weakness. The patient should follow the instructions of the pharmacist.

spironolactone belly fat

Additionally, taking Spironolactone pills in a higher dose might trigger stomach-related and metabolic issues.  The patient should avoid popping potassium pills while on this medication. High potassium levels might cause problems like muscle weakness or arrhythmia.

According to the studies, spironolactone has no impact on excess weight, unpredictable periods, or PCOS indications.

What Is Spironolactone Used For?

Spironolactone is the first-line treatment of New York Heart Association Class III-IV cardiovascular breakdown. Spironolactone is best for the management of edema in cirrhosis patients not responsive to sodium limitations.

Spironolactone has a few FDA-supported indications for which it’s recommended, including:

  • Cardiovascular complications
  • Edema is brought about by cardiovascular breakdown, liver infection, or kidney illness

It can treat Pre-operatively essential hyperaldosteronism. Furthermore, essential hyperaldosteronism and adrenal adenomas are treated with spironolactone. Medical procedures are not beneficial for these patients.

Moreover, it has benefits for patients with macronodular adrenal hyperplasia. Spironolactone is the first choice for combination treatment in hypertension—furthermore, nephrotic complications when diuretics are not sufficient to treat the condition.

It has anti-androgenic properties, which prompts massive effects. Additionally, it is utilized off-label in the treatment of hirsutism, female baldness, and acne vulgaris.

Additionally, it is for:

  • treating hypertension
  • forestalling low potassium
  • bringing down levels related to hyperaldosteronism (unreasonable discharge of aldosterone)

Notwithstanding its diuretic impacts, spironolactone obstructs androgen receptors. This implies that it can diminish the effects of testosterone in the body.

Due to this extraordinary impact, spironolactone is frequently utilized off-name for conditions that include abundance testosterone. A portion of these have:

  • skin break out
  • abundance facial or body hair development in ladies
  • female baldness
  • polycystic ovary disorder (PCOS)

Related: How Herbalife and PCOS Connected?

Lastly, due to the antiandrogenic effects of spironolactone, it has benefits for transgender female patients. The sole reason is its low expense and reduced hair growth.

How To Take Spironolactone Accurately?

Take spironolactone by mouth, as explained by your doctor. Although you might experience stomach upset, you should take it with food or milk. It is ideal for taking your meal promptly during the day, not later than 6 pm.

The sole reason is that you don’t have to get up at night to pee continuously. Make sure you get a complete consultation regarding this medication by a pharmacist or any health care provider; otherwise, you will end up worrying about spironolactone belly fat loss or gain.

If you utilize this medicine in syrup dosage form, shake the jug a long time before each portion. Cautiously measure the dose using a measuring gadget/spoon. Try not to utilize a kitchen spoon since you may not get the correct dose. You might take the syrup with or without food. However, pick one way and take it the same way with each portion.

spironolactone belly fat

Besides the accurate timing, the dose depends on your ailment and response to the treatment. In kids, the quantity is calculated according to body weight. Furthermore, take this medicine routinely to get the most advantage from it.

Make sure to utilize it at the equivalent times every day as instructed. Continue to take this drug regardless of whether you feel good. A great many people with hypertension don’t feel wiped out.

Take this medicine precisely as suggested. Try not to build your portion, take it more frequently than recommended, or quit utilizing this medication without first counseling your primary care physician.

Your condition might turn out to be more regrettable when the drug is unexpectedly halted. Spironolactone emotional side effects kick in if the medication dose is not accurate.


To sum up, Spironolactone weight loss can be beneficial only if the doctor recommends this therapy. Although the drug is useful for various serious health concerns, it affects excess belly fat.

The reason can be that the spironolactone loses belly fat by eliminating excess toxins and body water. There is no evidence of spironolactone weight gain. Although, there might be some positive clinical studies regarding spironolactone and cellulite.

If you consider opting for spironolactone for weight loss, the first step should be to go through the article and consult a doctor to know what you’re getting into.

Self-medication yourself can be harmful and can have deleterious effects on your body. So, it’s better to be safe than sorry.


Does spironolactone reduce belly fat?

Yes, of course! Spironolactone might help to reduce extra weight. Spironolactone belly fat reduction has no clinical approach, but many patients report weight loss. This is considered a positive outcome.

Does spironolactone make you gain or lose weight?

Spironolactone can rarely gain weight. There is no connection found between spironolactone weight gain and cellulite. Although there are some improved cases of cellulite, there is no clinical evidence.

Will my boobs grow on spironolactone?

Yes! In some cases of high doses, there has been breast enlargement in women. It is temporary, but it is possible.

Does spironolactone suppress appetite?

There is a reported side effect of spironolactone loss of appetite. Technically, if you are not eating much, you will reduce weight.

Why does spironolactone make you gain weight?

Weight gain is a side effect if you’re not taking medicine according to the recommended dose or an underlying health issue.

Does Spironolactone change body shape?

There are no definite changes in the body shape. But around 26% of women have reported changes in breast size.

How to safely stop taking spironolactone?

The best way to stop any medication is to consult your doctor. It is possible that if you are on a high dose, your doctor will taper to a lower dose. Spironolactone weight gain after stopping the medicine is harmful. Withdrawal symptoms of spironolactone can be detrimental and life-threatening.

How much water should I drink when taking spironolactone?

It would help if you took every dose of spironolactone with a full glass of water. Make sure your body is well hydrated throughout the day.

Can Spironolactone cause gastritis?

No! It might cause stomach upset, but you can take medicine with meals if you feel comfortable.

Wholesomealive.com -a blog about Healthy Living