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All You Need To Know to Lose Effexor Withdrawal Weight Gain

Good health is one of the most precious things one can ever possess. But does health only implies to your physical health? No! It certainly does not.

While we say health, it comprises both physical and mental health. But is our mental health given the same importance as physical health? In many cases, the answer would be negative since many have a tendency to avoid it.

However, in recent days the importance of mental health has taken a turn and people are now getting conscious about it and are also receiving treatment in severe cases.

In the treatment of depression, generally, antidepressants are prescribed. Today, in this article I will introduce you to an antidepressant named ‘Effexor’ and will also let you know about the Effexor withdrawal weight gain.

So, let’s look into the details!

Table of Content

What is Effexor?

Effexor is the brand name for Venlafaxine which is an SNRI (serotonin-norepinephrine reuptake inhibitor) and is regularly used as an antidepressant.

This is usually prescribed if a person suffers from:

  • Panic attacks
  • Anxiety
  • Social phobia
  • Depression

Effexor mainly works by balancing the levels of certain hormones called norepinephrine and serotonin in your brain. By doing this, it helps in increasing your energy level, uplifting your mood, and aids in restoring happiness in your everyday life.

Effexor Dose

There are two types of Effexor that might be prescribed:

Extended-release: 37.5 -75mg/day PO, 1 time initially and might be increased up to 250mg/day if needed.

Immediate-release:  75mg/day in divided doses (q8-12hr) initially and might be increased up to 375mg/day if required.

Effexor Side Effects

You might be wondering, ‘are there any Effexor side effects?’ Unfortunately, yes!

So, what are the most common side effects of Effexor? Take a look:

  • Nausea
  • Dizziness
  • Loss of appetite
  • Drowsiness
  • Unusual sweating
  • Nervousness
  • Blurred vision

If you are encountering any of these effects constantly then consider consulting your doctor right away.

What does Effexor Withdrawal Mean?

Understanding the concept of Effexor withdrawal or Venlafaxine withdrawal is very important.

At this point, while you quit consuming antidepressants like Effexor, Paxil, or any medications of this type, you may build up a state that is known as, ‘antidepressant discontinuation syndrome’.

This situation happens in around 20% of patients who have been consuming antidepressant medicines for a minimum of one month and a half and afterward quits suddenly.

On account of Effexor, withdrawal manifestations may incorporate the following:

  • Vertigo
  • Nausea
  • Vomiting
  • Anxiety
  • Dizziness
  • General restlessness
  • Symptoms like flu
  • Fatigue
  • Depression and mood swings
  • Headache
  • Spasms of muscle

Psychological Effects of Cutting off Effexor

The time somebody quits consuming an antidepressant, the unexpected change affects the brain’s chemical makeup. Thus, now and again ‘antidepressant discontinuation syndrome’ may prompt a psychological break.

Since Effexor withdrawal may likewise result in some disarray, specialists suggest that patients should restrain from operating vehicles or heavy machinery while on the verge of coming off the medicine.

Suspending Effexor may likewise exhibit these impacts:

  • Psychosis
  • Confusion
  • Anxiety or depression
  • Short-lived narcolepsy
  • Cataplexy
  • Issues with focus

Again, in the event, that you experience these uncommon, yet severe manifestations while experiencing withdrawal, ask for clinical help immediately:

  • Mania
  • Suicidal feelings
  • Delirium

Effexor withdrawal symptoms come into the scene rapidly and can be eased very quickly by consumption of the drug.

On the off chance, that you prefer quitting the medication for good, request your physician to assist you with building up a plan to slowly reduce your consumption of the medicine. Coming off Venlafaxine successfully may sound difficult and might cause you a bit of uneasiness but eventually, you will be able to do it. Other than these you can try out supplements like Synapse XT to improve the overall function of your brain.

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Association Between Effexor With Weight Change

What is Effexor weight gain? Or can stopping antidepressants cause weight gain? – are some certain confusion that concerns people who want to start using an antidepressant. Again, losing weight after stopping venlafaxine is also seen in some individuals.

Well, these questions are subject to controversy as a lot of variations are noticed in Effexor reviews. There are people who encounter weight gain while on antidepressants while some complained to have a weight pick up after they discontinued it.

So, does Effexor cause weight gain? Let’s see!

Weight Gain While Consuming Effexor

Venlafaxine, as other SNRIs, frequently prompts weight pick up subsequent to long-term consumption. A few patients put on weight within 10 weeks of beginning the treatment, whereas others experience this a bit later.

Weight Gain While Consuming Effexor

Patients who put on weight after short-term Effexor use, start to lose weight after it is suspended. Nonetheless, the individuals who pick up the weight on the basis of long-term medication, find it hard to lose weight even after the discontinuation of the drug.

Weight gain from using Venlafaxine for a short time is believed to be caused due to appetite changes. Patients consume more food because of their symptom improvement as a result of the treatment, or ‘Effexor euphoria’ brought about by the recreational benefits of the medication.

Long-term weight picks up on Effexor is generally connected to hormonal and metabolic impacts of the medicine on the body, which includes its effect on the thyroid hormone along with enhancing the craving for the carb.

Factors Influencing Effexor weight gain

Effexor influences various body systems, prompting a few negative impacts. In this specific circumstance, impacts on the gastrointestinal system, appetite, the endocrine system, etc regulates the effect of the medicine in your body.

Appetite Changes

Perhaps the most fundamental reason behind Effexor weight pick up is the alternation in hunger at the time of treatment. A patient suffering from any sort of ‘anxiety mediated disorder’ may experience the ill effects of diminished hunger because of such an issue or eat enthusiastically.

Hence, at the time, the patient notices improvements as a result of the treatment, it might either stifle or enhance craving dependent on past manifestations.

Also, recuperation from despondency problems might be related to the upgrade in the food taste,  expanded social eating, and so on which may stimulate the patient to consume more food and in this manner acquire more weight.

Notwithstanding the moderation of disease manifestations, Effexor may influence the ‘appetite regulation system’ in the body, incorporating ‘tumor necrosis factor’ and ‘leptin’. This prompts an expansion in craving, which is ordinarily noticed with long-term consumption of Effexor.

Carb Yearning

Patients on Effexor have complained that their enhanced yearning for sweet and fatty nourishments. These yearnings may likewise be aggravated by the impacts of Effexor on ‘tumor necrosis factor’, and on ‘leptin’.

Along with these desires for sweet and fatty nourishments, disturbance of these previously mentioned systems due to the treatment additionally adds to the expanded occurrence of other metabolic problems like hypertension, diabetes mellitus, and so on in the long haul.

Disturbance of glucose digestion in diabetes and interruption of salt equilibrium related to hypertension further triggers yearnings for fatty nourishments, and carbs, transforming the impact into a ‘metabolic vicious cycle’.

Hormonal Effects

Effexor meddles with the endocrine equilibrium of the body. It regulates the metabolism system concerning the thyroid hormone, subsequently influencing craving as well as the use of carbs, and fats for energy creation inside the body.


In spite of being rare, edema, particularly of the tissues in the periphery, is found in certain patients with long-term Effexor consumption. This edema might contribute to the weight pick up subsequent to venlafaxine use.

The thyroid hormone plays a vital role in maintaining the body weight, and any alteration of this system prompts a huge body change.

Ways to Lose Weight

There are certain ways of losing weight which you may gain as a side effect of Effexor or any other antidepressant. Take a look below:

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Consume Food Often But in Smaller Quantity

As Effexor increases your appetite, you may crave food constantly. So, in this case, eat food more frequently but in smaller quantities.

Think Before Consuming Sodium Enriched Food

Excessive intake of sodium should be avoided while you are on an antidepressant as this may lead to hypernatremia. Again, you must be aware of hyponatremia as well since this condition may lead to health issues like dizziness, lethargy, nausea, and confusion during the course of antidepressants.

Enhance Potassium Intake

Potassium is helpful in flushing out sodium. So, if you have gained weight subsequent to medication consider having potassium enriched food like avocados, bananas, coconut water, and so on.

Get a Profound Rest

Good sleep is important while you are trying to get into shape. Remaining awake at night might make you crave food and add up to your present weight.

Remain Active

Doing exercises is always good for health. If you were not used to doing physical activities, then start it right away. Low-intensity exercises like yoga and walking will also help you to reduce the weight you gained.

Prevention of Weight Change

Venlafaxine prompts weight pick up following prolonged use, and once in a while weight reduction in case of short-term use. Notwithstanding, numerous means might be taken to moderate this change along with the metabolic problems noticed in the patient:

  • Make an increment in the physical activity
  • Can consider switching to another drug
  • Take behavioral therapy.


Mental health bears great significance while it comes to maintaining a good quality of life. A happy mind is important to stay healthy overall.

Antidepressants might have some side effects but generally, the benefits surpass the side effects. If you are concerned about your weight gain due to antidepressants like Effexor, then consider trying out different ways of losing weight.

In case you are not comfortable with physical activity, then you might shift your preference towards certain weight reduction supplements. A weight reduction supplement called ‘Leptitox’ may help you in this case.

However, I hope this article regarding Effexor withdrawal weight gain will help you to understand well the association between Effexor and weight gain and thus guide you if you are in need of consuming this medicine.

The FAQs About Effexor Withdrawal Weight Gain

Antidepressants can be a reason for your weight gain. Many people do not possess proper knowledge about the use, dosage, and side effects of antidepressants. Thus a lot of queries arise while it comes to these medicines. And also a proper idea about the basics of these medicines is very important.

Following are some most asked questions regarding Effexor and antidepressants.

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