Can Amoxicillin Raise Your Blood Sugar or It’s Just a Myth?

Are you a person with diabetes worried about taking antibiotics and thinking, can amoxicillin raise your blood sugar? Find all the answers in this article.

Diabetes is a notoriously tricky condition. One of the reasons behind this is that it never comes alone. It brings many other health complications like nerve damage, kidney problems, and infections. 

can amoxicillin raise your blood sugar
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For those who have type 2 diabetes, infections are a very common ailment. The primary way to combat this is through antibiotics. But some antibiotics can raise your blood sugar, putting you at higher risk. 

Can You Reverse Type 2 Diabetes

So which antibiotics are safe and which aren’t? How do you tell if your antibiotic is causing raised blood sugar?

By the end of this article, I’ll have answered all your questions about antibiotics and diabetes. So let’s begin.

Does Amoxicillin Raise Blood Sugar?

Amoxicillin is a very commonly prescribed antibiotic. It belongs to the same family as Penicillin, the first-ever antibiotic discovered by Alexander Fleming in 1928. It is a broad-spectrum antibiotic used for treating a wide range of infections. As for whether Amoxicillin raises blood sugar or not, the answer is a bit nuanced. 

Antibiotics are not historically known to cause disturbances in blood sugar levels. But as our understanding of how the body metabolizes glucose has developed, a link between the use of antibiotics and a higher risk of diabetes has begun to emerge. 

Recent studies have concluded that taking certain antibiotics may increase the risk of developing diabetes. However, the exact cause behind this is still unknown. More investigative studies are now underway to find out exactly how antibiotics affect the body’s glucose metabolism.

So the short answer is yes. Theoretically, a tiny group of people may be vulnerable to blood sugar disturbances caused by Amoxicillin or similar drugs. This may be due to peculiarities or genetic predispositions. There is simply not enough evidence yet to prove or disprove this.

How Can Amoxicillin Raise Your Blood Sugar?

Scientists don’t yet know how exactly antibiotics affect the blood glucose levels in the body. But the basic idea is that they affect the bacteria in your gut. 

What is gut bacteria?

The intestinal flora consists of 300 to 500 species of bacteria that live within your gastrointestinal tract—the genetic content sum up to a staggering 2 million genes. Even more mind-boggling is that the total number of intestinal bacteria in the gut is approximately 10 times the total number of cells in the human body. 

These bacteria perform a myriad of functions like fighting off harmful pathogens, breaking down indigestible food components, and maintaining the intestinal lining. But recent studies have uncovered that the parts of the intestinal flora may be even more intricate than previously thought.

It is now believed that gut bacteria play an essential role in the metabolism of glucose or sugars. They might be responsible for processing f complex carbohydrates into glucose and the assimilation of glucose by the body.

How does Amoxicillin fit into the picture?

Amoxicillin is a broad-spectrum antibiotic. Taking an excessive dose of antibiotics or using them for an extended period may cause severe damage to your gut bacteria. This, in turn, could disrupt the functions of your digestive system. By extension, it could also potentially cause blood sugar imbalances leading to high blood sugar and diabetes.

The mechanism of how antibiotics like amoxicillin might hamper intestinal flora and cause high blood sugar is still unknown. But studies have shown the interrelation between antibiotic use and increased risk of type 2 diabetes.

Which Antibiotics can raise Blood Sugar?

Modern antibiotics are of many different types. Doctors prescribe these according to the type of infection you are facing. If you still have the question, can amoxicillin raise your blood sugar? It’s better to learn in detail. 

You’ll find that various types of antibiotics are prescribed for different reasons. Some of these can be bought over-the-counter, while others are not recommended save for the most critical situations. 

Not all of these will affect your blood sugar. So, it’s essential to know which antibiotics will raise your blood sugar and which won’t.

Fluoroquinolones are a family of antibiotics generally used to treat respiratory tract infections and UTIs. Among the drugs belonging to this family are Ciprofloxacin, Levofloxacin, Moxifloxacin, and Ofloxacin are the most common. 

Recent studies have shown that high or prolonged dosages of Fluoroquinolones may cause numerous serious side effects. Chief among them is the probability of causing erratic swings in blood sugar levels. These sudden shifts, if unchecked, may cause severe hyperglycemia or hypoglycemia. Both of which are especially harmful to diabetics. 

These findings have exposed how certain antibiotics may actually increase the risk of type 2 diabetes. Still, more conclusive studies are required to corroborate these claims. 

What Other Drugs can raise Blood Sugar?

People suffering from diabetes often suffer from multiple illnesses at once. If you are a diabetic, chances are you are taking additional medication for other problems as well. These health problems are most often attributed to obesity. 

Problems like heart problems, high cholesterol, hypertension, kidney problems, inflammation, arthritis, etc., are closely related to Diabetes. The medication for these various illnesses may also affect your blood sugar levels too. 

List of drugs that raise blood sugar:

Statins for High Cholesterol

Simvastatin, Rosuvastatin, etc., are examples of a group of drugs called statins. These drugs are mainly used to lower LDL levels and control blood cholesterol. They are essential to prevent heart disease and stroke. But a side-effect of this drug is that it inhibits the function of insulin. 

Insulin is a hormone in your body that allows the uptake of glucose into the cells from the bloodstream. Thus, by hampering the function of insulin, Statins raise the blood sugar level.

Beta-Blockers for Heart Problems

Beta-blockers are a large group of drugs that are used to treat various cardiac illnesses. They are used to treat a variety of conditions like arrhythmia and anxiety. Common examples of beta-blockers are Atenolol and Metoprolol.

Some beta-blockers can raise blood sugars. But there are alternatives. Carvedilol is a beta-blocker that does not affect blood sugar levels.

Corticosteroids for Inflammatory Diseases

Corticosteroids are used to treat any inflammatory condition of the body. If you have ever had asthma, the inhaler that you used actually contained a corticosteroid. In the same way, corticosteroids are used to treat acute inflammation, arthritis, allergies, COPD, etc. 

High doses of steroids in the blood can actually block the pancreas from secreting insulin. Small amounts like inhalers or creams are not enough to cause any problems. But high doses that are injected or ingested may cause a significant increase in blood glucose levels.

Diuretics for Blood Pressure

Diuretics are used to increase urine output. They can be used to treat kidney diseases and also lower blood pressure. Hydrochlorothiazide and Chlorthalidone are diuretics commonly prescribed for high blood pressure. 

Diuretics can increase the levels of potassium in your blood, This results in a condition called hyperkalemia. In this state, the pancreas cannot secrete insulin properly. This results in insulin deficiency and ultimately high blood sugar.


Certain antidepressants like Fluvoxamine, Mirtazapine, Sertraline, etc. can cause high blood sugar if taken in high doses. 

High doses of these medications taken over a prolonged period have been associated with high blood sugar and increased risk of diabetes, However, low daily doses do not cause any adverse effects.

What to do if Your Meds are Affecting Your Blood Sugar?

So far in this article, you have come to learn about different drugs that may cause problems with blood sugar. Odds are, you might be taking some of them right now. So what should you do? You might think to stop taking the meds altogether. But as I will explain, that might not be the best course of action. 

Here are the things you should do if your meds are hampering your blood sugar:

Pause your dosage

Stop taking your meds for the time being. If your meds are causing blood sugar spikes, continuing to take the drug puts you at risk of hyperglycemia. 

Extremely high or low blood sugar may lead to shock or even coma. So it’s best to take a little break until you get things sorted out with your doctor.

Consult with your physician

If you are facing any trouble with your prescribed medication, the first thing you should do is call your doctor. Explain the side effects or reactions as clearly as possible. Your doctor will either adjust the dosage of the meds or replace them altogether.

ask your doctor Can Amoxicillin Raise Your Blood Sugar
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Your doctor may still prescribe meds that have some side effects. This is because the doctor makes the decision based on your current condition and health. In these cases, the doctor chooses the potential major benefit over the drawbacks.

Never stop or change your medication by yourself. Always consult your doctor before making any changes to your prescription. 

Take care of your health

You should also look at other factors that may be influencing your blood sugar. Avoid taking sugar rich foods and take proper exercise. External actors like smoking, alcohol, stress, junk food, etc. can interfere with your medication. 

So try to make the necessary adjustments to your lifestyle to promote good health. Otherwise, you may end up asking Can Amoxicillin Raise Your Blood Sugar.

How to Choose which Meds to take

Just because some meds can raise your blood sugar doesn’t necessarily mean that they are harmful. If your doctor prescribes you these meds, that means you need them to treat whatever condition that you have. So it’s important to talk to your doctor about which meds to take and how to safely take them.

Always inform your doctor about any new medication that you take. Even a simple over-the-counter cough syrup for a cold might cause your blood sugar levels to spike. So share any and all medications that you might take with your physician.

Try to learn about the meds that you take. A quick search on the web will help you understand your medication better and also how to use them safely. If you are facing problems with your current prescription, it will also help you make an informed decision about switching to alternatives.  

If you face any serious side effects or complications, contact your doctor immediately. You may also ask your doctor for alternatives to your current prescription.


Can antibiotics raise blood sugar?

While most antibiotics have no effect on blood sugar, some types of antibiotics can raise blood sugar levels. 

Fluoroquinolones are a family of antibiotics that are known to cause swings in blood sugar levels.

Which antibiotics are safe for diabetes patients?

Almost all antibiotics are safe for people suffering from diabetes. Your doctor will prescribe the appropriate antibiotics for your illness. 

Taking the correct prescribed medicine with the right dosage pretty much guarantees that the drug will be safe for your body.

Do antibiotics help with type 2 diabetes?

Antibiotics are drugs that kill harmful microorganisms that cause disease in the body. Diabetes on the other hand is a metabolic disorder where the body cannot absorb the sugar present in the blood.

So antibiotics do not have any direct correlation with diabetes.


So long story short, Can Amoxicillin raise your blood sugar? The answer is probably yes. 

But in this article, you’ve already learned that there is more to the story than just that. Research is currently underway to fully understand just how antibiotics affect blood sugar and diabetes. So, we may soon get all the answers.

Diabetes can be difficult. Infections can make it harder. But a proper combination of diet, dose, and discipline can life much easier. So make sure that you are taking a balanced diet and exercise along with your medication. 

Muhtasim Munir

Muhtasim Munir

As a doctor in the making, I feel fascinated by the advancements and expansion of medical science. This fuels my passion for trying to follow a health-conscious lifestyle. I love writing and sharing thoughts and ideas with the people I care about. If my work can reach out and help people to enjoy a healthy, happy life it will be an honor for me. Muhtasim Munir MBBS (3rd year) Armed Forces Medical College -a blog about Healthy Living