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What Is the Best Time to Take Prozac for Weight Loss?

There is a link between weight changes and many antidepressants. As opposed to other medications that may cause weight gain as a side effect, Prozac may prevent weight gain in the short term. Depression and panic-related disorders are usually treated with it in adults as well as in children.

Many people also take Prozac to reduce their weight. Our main concern is, what is the best time of day to take Prozac for weight loss?

It is always recommended to take Prozac in the morning or early part of the day. In addition, taking Prozac at night or in the evening is not problematic either. There will be no difference in Prozac’s efficiency based on when you take it.

Then, why is the morning dose always recommended? Keep analyzing all the information below to find out.

Table of Content

Best Time of Day to Take Prozac for Weight Loss?

People often ask, when to take Prozac am or pm. It is generally recommended that Prozac be taken in the morning or any other time of the day if not in the morning. The consumption of this antidepressant should not be done at the end of the evening or night. The effects of taking Prozac at night do not necessarily lead to severe health problems. But, doctors typically recommend taking it during the day.


The side effects caused by Prozac are one of the major reasons it is recommended during the daytime. The two most common side effects of Prozac are insomnia and dry mouth. Even if you do not take any antidepressants, you are likely to experience dry mouth at night. Prozac taken at night can worsen dry mouth, whereas taking it in the morning can alleviate it. In the morning, water intake is usually higher than at night, which prevents dryness during the day.

On the other hand, insomnia can only cause discomfort during the night, when patients want to sleep peacefully. Prozac should be taken in the morning, so this side effect should be relieved by the end of the day.

Patients who take Prozac may also experience fatigue and drowsiness as side effects. In such cases, taking it in the morning can be challenging. Try to take this medication about two to three hours before you go to bed at night. You will feel less affected by these side effects at this time.

Further, if you are unsure whether Prozac is effective with varying timings, let me clarify that it will produce the same recovery effects whether you take it in the morning or at night. Timing recommendations are intended to alleviate its side effects.

Prozac and Weight Gain

You may have a question, does Prozac cause weight loss? Prozac can be prescribed to treat weight gain. In studies, Prozac caused significant weight loss in patients with depressive disorders taking this medication. This is due to the action of the antidepressant Prozac on the appetite suppressant serotonin.

It was found that patients on Fluoxetine lost 13 pounds, almost twice as much as they did on Xenical (6 pounds) during the same period. Similarly, Fluoxetine-treated patients lost an average of 11 pounds over 27 weeks, while Meridia-treated patients lost less than 10.

It is important to keep in mind that Prozac does not always lead to weight loss. If taken for a prolonged period of time, it can even result in weight gain. It is because spirit drinks are usually high in calories that are the main cause of weight gain. In addition, Prozac has a considerably longer half-life, making it harder to eliminate Prozac quickly. The antidepressant remains in the body and can cause mass gain as a consequence of prolonged use.

How Does Prozac Work?

Antidepressants like Prozac belong to the selective serotonin reuptake inhibitor family. These medications have an impact on neurotransmitters, which are chemical messengers in the brain. Serotonin is a neurotransmitter linked to emotion, sleep, and appetite. A serotonin uptake pump returns some of the serotonin that has been released by a nerve cell to the brain.


Prozac stops serotonin from being reabsorbed, increasing its continuing availability. The persistent supply of Serotonin aids in appetite regulation, therefore restoring normal levels may eventually result in weight loss.

The effectiveness of Prozac lies in its ability to reduce appetite, which in turn promotes weight loss. Additionally, it makes the person feel full without eating much. As a result, Prozac can increase satiety.

Despite this, there is no strong evidence that Prozac contributes to weight loss. But researchers believe it can help with short-term obesity (obesity that may occur due to depression or some other possible reason) recovery.

How to Use Prozac for Weight Lose?

It is always recommended to combine Phentermine with Prozac in a modest dose (10–20 mg) for effective weight loss. In order to maintain effectiveness, Phentermine needs to be accompanied by another medication otherwise effectiveness in weight loss may be lost.


As a result of the second medication, appetite-suppressing neurotransmitters are present for a longer period of time, prolonging the period of satiety. The interaction also reduces the negative effects of the drugs. Because the appetite is suppressed for a longer period of time, fewer calories are consumed, causing weight loss to occur sooner than would be expected using conventional methods.

In spite of the fact that the second drug is also an antidepressant, the combination of the two has nothing to do with depression.

Does Prozac Cause Weight Gain?

The patient has also reported weight gain when taking Prozac. According to our earlier discussion, Prozac works by increasing serotonin, which means it maintains the appetite of the body. 

In the case of a patient who has lost weight due to depression and is now taking the antidepressant Prozac. How will things turn out now? As soon as the person begins taking Prozac, his appetite will return to normal and he will start feeding according to his needs. Weight gain can result from this increased calorie intake. There is still a lack of understanding of the detailed mechanism involved in Prozac weight gain.

In addition to Prozac, certain other antidepressants can also lead to weight gain. Antidepressant Zoloft, for example, is more likely to cause weight gain when compared to Prozac. 

What Is the Lowest Dose of Fluoxetine?

To treat patients with acute symptoms or for children, fluoxetine 10 mg is the lowest dose. It is possible to increase this dose to 80 mg per day according to the severity of the condition.

Fluoxetine (Prozac) Side Effects

If you experience an allergic reaction to fluoxetine (hives, difficult inhaling, swelling in your face or neck) or a severe skin reaction (fever, throat pain, itchy eyes, skin pain, blistering ,and peeling rash on skin), seek medical attention immediately.


Some common Fluoxetine side effects include:

  • Insomnia
  • Headache
  • Drowsiness
  • Visual alterations
  • Convulsions
  • Anxiety
  • Irritation
  • Lethargy
  • Weakness
  • Tiredness
  • Peptic discomfort
  • Reduced appetite
  • Vomiting or nausea
  • Diarrhea
  • Dry mouth
  • Fluctuations in weight
  • Flu
  • Decreased sexual drive

If taken at high doses for a long period of time, fluoxetine serious side effects can occur. These severe side effects include:

  • Blurred or tunnel vision with eye pain or swelling.
  • Sodium deficiency can also lead to headaches, fuzziness, disorientation, severe weakness, and loss of coordination.
  • Symptoms of severe nervous system damage.

Breast enlargement, chest discomfort, abnormal dreams, loss of taste, visual complications, and a feeling of warmth or warmth are some of the side effects of Fluoxetine in females.


Question: How long does it take to lose weight on Prozac?

Answer: Average weight loss of slightly more than 11 pounds has been observed in patients taking Prozac for 24 to 30 weeks. Depending on the severity of the condition and the patient’s physiological and medical conditions, this time can be increased.

Question: Is it better to take Prozac in the morning or at night?

Answer: The best time to take Prozac is in the morning. You may also take Prozac at any time throughout the day if you do not find it suitable to take it in the morning. You can also take it at night, its effectiveness will not be affected. The morning timing is recommended only to alleviate side effects like insomnia and dry mouth.

Question: Is Prozac an appetite suppressant?

Answer: Yes, Prozac is an appetite suppressant. Prozac is an antidepressant that belongs to the family of selective serotonin reuptake inhibitors. These medications affect neurotransmitters that control appetite, sleep, and emotions. This neurotransmitter control allows Prozac to suppress appetite.

Question: Is Prozac keeping me from losing weight?

Answer: There is a possibility that Prozac can lead you to gain weight rather than lose it. Prozac increases serotonin and maintains appetite, so if you have lost weight during the depression, you may be able to regain it. Furthermore, spirits drinks tend to be high in calories, so consuming too much Prozac can lead to weight gain.


What is the best time to take Prozac for weight loss? The best time to take Prozac is in the morning, whether you are losing weight or treating another disorder. During any part of the day, it is also suitable for consumption. Taking Prozac at night also won’t affect its effectiveness. The time recommendation is only for the relief of some common side effects, including insomnia and mouth dryness.

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